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Dysregulated lung stroma drives emphysema exacerbation by potentiating resident lymphocytes to suppress an epithelial stem cell reservoir.
Wang, Chaoqun; Hyams, Ben; Allen, Nancy C; Cautivo, Kelly; Monahan, Kiara; Zhou, Minqi; Dahlgren, Madelene W; Lizama, Carlos O; Matthay, Michael; Wolters, Paul; Molofsky, Ari B; Peng, Tien.
Affiliation
  • Wang C; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Zhongshan Institute for Drug Discovery, Chinese Academy of Sciences, Zhongshan 528400, China.
  • Hyams B; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Cardiovascular Institute and Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Allen NC; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Cardiovascular Institute and Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Cautivo K; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Bakar ImmunoX Initiative, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Monahan K; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Cardiovascular Institute and Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Zhou M; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Cardiovascular Institute and Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Dahlgren MW; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Bakar ImmunoX Initiative, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Lizama CO; Cardiovascular Institute and Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Matthay M; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Wolters P; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA.
  • Molofsky AB; Department of Laboratory Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Bakar ImmunoX Initiative, University of California, San Francisco, San Francisco, CA 94143, USA. Electronic address: ari.molofsky@ucsf.edu.
  • Peng T; Department of Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Cardiovascular Institute and Division of Pulmonary, Critical Care, Allergy and Sleep Medicine, University of California, San Francisco, San Francisco, CA 94143, USA; Bakar ImmunoX Initiative, University of
Immunity ; 56(3): 576-591.e10, 2023 03 14.
Article in En | MEDLINE | ID: mdl-36822205
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Emphysema / Pulmonary Disease, Chronic Obstructive / Emphysema Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Type: Article Affiliation country: China
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pulmonary Emphysema / Pulmonary Disease, Chronic Obstructive / Emphysema Limits: Animals / Humans Language: En Journal: Immunity Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Type: Article Affiliation country: China