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The utility of a type 2 diabetes polygenic score in addition to clinical variables for prediction of type 2 diabetes incidence in birth, youth and adult cohorts in an Indigenous study population.
Wedekind, Lauren E; Mahajan, Anubha; Hsueh, Wen-Chi; Chen, Peng; Olaiya, Muideen T; Kobes, Sayuko; Sinha, Madhumita; Baier, Leslie J; Knowler, William C; McCarthy, Mark I; Hanson, Robert L.
Affiliation
  • Wedekind LE; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA. Lauren.Wedekind@linacre.ox.ac.uk.
  • Mahajan A; Nuffield Department of Medicine, University of Oxford, Oxford, UK. Lauren.Wedekind@linacre.ox.ac.uk.
  • Hsueh WC; Wellcome Centre for Human Genetics, University of Oxford, Oxford, UK.
  • Chen P; Genentech, San Francisco, CA, USA.
  • Olaiya MT; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA.
  • Kobes S; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA.
  • Sinha M; College of Basic Medical Sciences, Jilin University, Changchun, China.
  • Baier LJ; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA.
  • Knowler WC; School of Clinical Sciences, Monash University, Clayton, VIC, Australia.
  • McCarthy MI; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA.
  • Hanson RL; Phoenix Epidemiology and Clinical Research Branch, National Institute of Diabetes and Digestive and Kidney Diseases, National Institutes of Health, Phoenix, AZ, USA.
Diabetologia ; 66(5): 847-860, 2023 05.
Article in En | MEDLINE | ID: mdl-36862161

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Adolescent / Adult / Child / Child, preschool / Humans Language: En Journal: Diabetologia Year: 2023 Type: Article Affiliation country: United States

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Diabetes Mellitus, Type 2 Type of study: Etiology_studies / Incidence_studies / Observational_studies / Prognostic_studies / Risk_factors_studies / Systematic_reviews Limits: Adolescent / Adult / Child / Child, preschool / Humans Language: En Journal: Diabetologia Year: 2023 Type: Article Affiliation country: United States