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SARS-CoV-2 spike protein induces IL-18-mediated cardiopulmonary inflammation via reduced mitophagy.
Liang, Shuxin; Bao, Changlei; Yang, Zi; Liu, Shiyun; Sun, Yanan; Cao, Weitao; Wang, Ting; Schwantes-An, Tae-Hwi; Choy, John S; Naidu, Samisubbu; Luo, Ang; Yin, Wenguang; Black, Stephen M; Wang, Jian; Ran, Pixin; Desai, Ankit A; Tang, Haiyang.
Affiliation
  • Liang S; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Bao C; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Yang Z; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Liu S; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Sun Y; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Cao W; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
  • Wang T; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Schwantes-An TH; Department of Cellular Biology & Pharmacology, Herbert Wertheim College of Medicine, Miami, FL, USA.
  • Choy JS; Department of Environmental Health Sciences, Robert Stempel College of Public Health and Social Work and Center for Translational Science, Florida International University, Port St. Lucie, FL, USA.
  • Naidu S; Department of Medical and Molecular Genetics, Indiana University School of Medicine, Indianapolis, IN, USA.
  • Luo A; Department of Biology, The Catholic University of America, Washington, DC, USA.
  • Yin W; Krannert Institute of Cardiology, Department of Medicine, Indiana University, Indianapolis, IN, USA.
  • Black SM; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Wang J; College of Veterinary Medicine, Northwest A&F University, Yangling, Shaanxi, China.
  • Ran P; State Key Laboratory of Respiratory Disease, National Clinical Research Center for Respiratory Disease, Guangdong Key Laboratory of Vascular Disease, Guangzhou Institute of Respiratory Health, The First Affiliated Hospital of Guangzhou Medical University, Guangzhou, Guangdong, China.
  • Desai AA; Department of Cellular Biology & Pharmacology, Herbert Wertheim College of Medicine, Miami, FL, USA.
  • Tang H; Department of Environmental Health Sciences, Robert Stempel College of Public Health and Social Work and Center for Translational Science, Florida International University, Port St. Lucie, FL, USA.
Signal Transduct Target Ther ; 8(1): 108, 2023 03 09.
Article in En | MEDLINE | ID: mdl-36894537
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / COVID-19 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Signal Transduct Target Ther Year: 2023 Type: Article Affiliation country: China
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spike Glycoprotein, Coronavirus / COVID-19 Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Signal Transduct Target Ther Year: 2023 Type: Article Affiliation country: China