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Potency ranking of pyrrolizidine alkaloids in metabolically competent human liver cancer cells and primary human hepatocytes using a genotoxicity test battery.
Haas, Manuel; Wirachowski, Karina; Thibol, Lea; Küpper, Jan-Heiner; Schrenk, Dieter; Fahrer, Jörg.
Affiliation
  • Haas M; Division of Food Chemistry and Toxicology, Department of Chemistry, RPTU Kaiserslautern-Landau, Erwin-Schroedinger-Str. 52, 67663, Kaiserslautern, Germany.
  • Wirachowski K; Division of Food Chemistry and Toxicology, Department of Chemistry, RPTU Kaiserslautern-Landau, Erwin-Schroedinger-Str. 52, 67663, Kaiserslautern, Germany.
  • Thibol L; Division of Food Chemistry and Toxicology, Department of Chemistry, RPTU Kaiserslautern-Landau, Erwin-Schroedinger-Str. 52, 67663, Kaiserslautern, Germany.
  • Küpper JH; Division of Molecular Cell Biology, Department of Environment and Nature Science, Brandenburg University of Technology Cottbus-Senftenberg, 01968, Senftenberg, Germany.
  • Schrenk D; Division of Food Chemistry and Toxicology, Department of Chemistry, RPTU Kaiserslautern-Landau, Erwin-Schroedinger-Str. 52, 67663, Kaiserslautern, Germany.
  • Fahrer J; Division of Food Chemistry and Toxicology, Department of Chemistry, RPTU Kaiserslautern-Landau, Erwin-Schroedinger-Str. 52, 67663, Kaiserslautern, Germany. fahrer@chemie.uni-kl.de.
Arch Toxicol ; 97(5): 1413-1428, 2023 05.
Article in En | MEDLINE | ID: mdl-36928417
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolizidine Alkaloids / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Arch Toxicol Year: 2023 Type: Article Affiliation country: Germany
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pyrrolizidine Alkaloids / Liver Neoplasms Type of study: Prognostic_studies / Risk_factors_studies Limits: Humans Language: En Journal: Arch Toxicol Year: 2023 Type: Article Affiliation country: Germany