Dynamic network-guided CRISPRi screen reveals CTCF loop-constrained nonlinear enhancer-gene regulatory activity in cell state transitions.

Luo, Renhe; Yan, Jielin; Oh, Jin Woo; Xi, Wang; Shigaki, Dustin; Wong, Wilfred; Cho, Hyunwoo; Murphy, Dylan; Cutler, Ronald; Rosen, Bess P; Pulecio, Julian; Yang, Dapeng; Glenn, Rachel; Chen, Tingxu; Li, Qing V; Vierbuchen, Thomas; Sidoli, Simone; Apostolou, Effie; Huangfu, Danwei; Beer, Michael A

Luo, Renhe; Yan, Jielin; Oh, Jin Woo; Xi, Wang; Shigaki, Dustin; Wong, Wilfred; Cho, Hyunwoo; Murphy, Dylan; Cutler, Ronald; Rosen, Bess P; Pulecio, Julian; Yang, Dapeng; Glenn, Rachel; Chen, Tingxu; Li, Qing V; Vierbuchen, Thomas; Sidoli, Simone; Apostolou, Effie; Huangfu, Danwei; Beer, Michael A.

bioRxiv ; 2023 Mar 09.

Article in En | MEDLINE | ID: mdl-36945628

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https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028945
https://dx.doi.org/10.1101/2023.03.07.531569

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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: BioRxiv Year: 2023 Type: Article

Fulltext

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10028945
https://dx.doi.org/10.1101/2023.03.07.531569

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PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies Language: En Journal: BioRxiv Year: 2023 Type: Article