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Targeting TLR4/3 using chlorogenic acid ameliorates LPS+POLY I:C-induced acute respiratory distress syndrome via alleviating oxidative stress-mediated NLRP3/NF-κB axis.
Jain, Siddhi; Saha, Pritam; Syamprasad, Nayadi Parambil; Panda, Samir Rajan; Rajdev, Bishal; Jannu, Arun Kumar; Sharma, Pawan; Naidu, Vegi Ganga Modi.
Affiliation
  • Jain S; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Sila village, Changsari, Guwahati, Assam 781101, India.
  • Saha P; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Sila village, Changsari, Guwahati, Assam 781101, India.
  • Syamprasad NP; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Sila village, Changsari, Guwahati, Assam 781101, India.
  • Panda SR; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Sila village, Changsari, Guwahati, Assam 781101, India.
  • Rajdev B; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Sila village, Changsari, Guwahati, Assam 781101, India.
  • Jannu AK; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Sila village, Changsari, Guwahati, Assam 781101, India.
  • Sharma P; Center for Translational Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Jane and Leonard Korman Respiratory Institute, Sidney Kimmel Medical College, Thomas Jefferson University, Philadelphia, PA 19107, U.S.A.
  • Naidu VGM; Department of Pharmacology and Toxicology, National Institute of Pharmaceutical Education and Research Guwahati, Sila village, Changsari, Guwahati, Assam 781101, India.
Clin Sci (Lond) ; 137(10): 785-805, 2023 05 31.
Article in En | MEDLINE | ID: mdl-36951146
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Distress Syndrome / NF-kappa B Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Sci (Lond) Year: 2023 Type: Article Affiliation country: India
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Respiratory Distress Syndrome / NF-kappa B Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Clin Sci (Lond) Year: 2023 Type: Article Affiliation country: India