Diagnosis, treatment and outcome of pheochromocytoma in a cat.
J Small Anim Pract
; 64(6): 415-420, 2023 06.
Article
in En
| MEDLINE
| ID: mdl-36977649
ABSTRACT
Pheochromocytoma in cats is a rare clinical condition characterised by the development of a secretory endocrine tumour that arises from the adrenal medulla. An 8-year-old castrated male, domestic shorthair cat was referred for further investigation of a 4-month history of progressive weight loss with normal appetite, polyuria/polydipsia, generalised weakness, and severe hypertension. Sonography and computed tomography of the abdomen disclosed a mass arising from the left adrenal gland. The contralateral adrenal gland was normal in size and shape. Results from a low dose dexamethasone suppression test and measurements of plasma aldosterone concentration and plasma renin activity ruled out a cortisol-secreting tumour and aldosteronoma. The clinical presentation made a sex-steroid secreting tumour unlikely. Increased plasma metanephrine and normetanephrine concentrations prioritised the differential diagnosis of pheochromocytoma. The cat underwent adrenalectomy of the left gland and histopathological diagnosis with immunohistochemical markers confirmed the diagnosis.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Pheochromocytoma
/
Cat Diseases
/
Adrenal Gland Neoplasms
Type of study:
Diagnostic_studies
Limits:
Animals
Language:
En
Journal:
J Small Anim Pract
Year:
2023
Type:
Article
Affiliation country:
Portugal