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Panitumumab vs Bevacizumab Added to Standard First-line Chemotherapy and Overall Survival Among Patients With RAS Wild-type, Left-Sided Metastatic Colorectal Cancer: A Randomized Clinical Trial.
Watanabe, Jun; Muro, Kei; Shitara, Kohei; Yamazaki, Kentaro; Shiozawa, Manabu; Ohori, Hisatsugu; Takashima, Atsuo; Yokota, Mitsuru; Makiyama, Akitaka; Akazawa, Naoya; Ojima, Hitoshi; Yuasa, Yasuhiro; Miwa, Keisuke; Yasui, Hirofumi; Oki, Eiji; Sato, Takeo; Naitoh, Takeshi; Komatsu, Yoshito; Kato, Takeshi; Hihara, Masamitsu; Soeda, Junpei; Misumi, Toshihiro; Yamamoto, Kouji; Akagi, Kiwamu; Ochiai, Atsushi; Uetake, Hiroyuki; Tsuchihara, Katsuya; Yoshino, Takayuki.
Affiliation
  • Watanabe J; Department of Surgery, Gastroenterological Center, Yokohama City University Medical Center, Yokohama, Japan.
  • Muro K; Department of Clinical Oncology, Aichi Cancer Center Hospital, Nagoya, Japan.
  • Shitara K; Department of Gastroenterology and Gastrointestinal Oncology, National Cancer Center Hospital East, Kashiwa, Japan.
  • Yamazaki K; Department of Immunology, Nagoya University Graduate School of Medicine, Aichi, Japan.
  • Shiozawa M; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
  • Ohori H; Division of Gastrointestinal Surgery, Kanagawa Cancer Center, Kanagawa, Japan.
  • Takashima A; Division of Medical Oncology, Japanese Red Cross Ishinomaki Hospital, Miyagi, Japan.
  • Yokota M; Department of Gastrointestinal Medical Oncology, National Cancer Center Hospital, Tokyo, Japan.
  • Makiyama A; Department of General Surgery, Kurashiki Central Hospital, Okayama, Japan.
  • Akazawa N; Department of Hematology/Oncology, Japan Community Healthcare Organization, Fukuoka, Japan.
  • Ojima H; Department of Gastrointestinal Surgery, Sendai City Medical Center, Sendai Open Hospital, Miyagi, Japan.
  • Yuasa Y; Department of Gastroenterological Surgery, Gunma Prefectural Cancer Center, Gunma, Japan.
  • Miwa K; Department of Gastroenterological Surgery, Japanese Red Cross Tokushima Hospital, Tokushima, Japan.
  • Yasui H; Department of Cancer Multimodel Therapy Center, Kurume University Hospital, Fukuoka, Japan.
  • Oki E; Division of Gastrointestinal Oncology, Shizuoka Cancer Center, Shizuoka, Japan.
  • Sato T; Department of Surgery and Science, Graduate School of Medical Sciences, Kyushu University, Fukuoka, Japan.
  • Naitoh T; Research and Development Center for Medical Education, Department of Clinical Skills Education, Kitasato University School of Medicine, Sagamihara, Japan.
  • Komatsu Y; Department of Lower Gastrointestinal Surgery, Kitasato University School of Medicine, Sagamihara, Japan.
  • Kato T; Division of Cancer Chemotherapy, Hokkaido University Hospital Cancer Center, Sapporo, Japan.
  • Hihara M; Department of Surgery, National Hospital Organization Osaka National Hospital, Osaka, Japan.
  • Soeda J; Japan Medical Affairs, Japan Oncology Business Unit, Takeda Pharmaceutical Company Ltd, Tokyo, Japan.
  • Misumi T; Japan Medical Affairs, Japan Oncology Business Unit, Takeda Pharmaceutical Company Ltd, Tokyo, Japan.
  • Yamamoto K; Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.
  • Akagi K; Department of Biostatistics, Yokohama City University School of Medicine, Yokohama, Japan.
  • Ochiai A; Division of Molecular Diagnosis and Cancer Prevention, Saitama Cancer Center, Saitama, Japan.
  • Uetake H; Pathology Division, Exploratory Oncology Research and Clinical Trial Center, National Cancer Center, Chiba, Japan.
  • Tsuchihara K; now with the Research Institute for Biomedical Sciences, Tokyo University of Science, Tokyo, Japan.
  • Yoshino T; National Hospital Organization, Disaster Medical Center, Tokyo, Japan.
JAMA ; 329(15): 1271-1282, 2023 04 18.
Article in En | MEDLINE | ID: mdl-37071094
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Bevacizumab / Panitumumab Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male Language: En Journal: JAMA Year: 2023 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Colorectal Neoplasms / Antineoplastic Combined Chemotherapy Protocols / Bevacizumab / Panitumumab Type of study: Clinical_trials / Prognostic_studies Limits: Aged / Female / Humans / Male Language: En Journal: JAMA Year: 2023 Type: Article Affiliation country: Japan