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Lineage-Specific Induced Pluripotent Stem Cell-Derived Smooth Muscle Cell Modeling Predicts Integrin Alpha-V Antagonism Reduces Aortic Root Aneurysm Formation in Marfan Syndrome Mice.
Nakamura, Ken; Dalal, Alex R; Yokoyama, Nobu; Pedroza, Albert J; Kusadokoro, Sho; Mitchel, Olivia; Gilles, Casey; Masoudian, Bahar; Leipzig, Matthew; Casey, Kerriann M; Hiesinger, William; Uchida, Tetsuro; Fischbein, Michael P.
Affiliation
  • Nakamura K; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Dalal AR; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Yokoyama N; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Pedroza AJ; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Kusadokoro S; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Mitchel O; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Gilles C; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Masoudian B; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Leipzig M; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Casey KM; Department of Comparative Medicine (K.M.C.), Stanford University School of Medicine, CA.
  • Hiesinger W; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
  • Uchida T; Second Department of Surgery, Yamagata University Faculty of Medicine, Japan (T.U.).
  • Fischbein MP; Department of Cardiothoracic Surgery (K.N., A.R.D., N.Y., A.J.P., S.K., O.M., C.G., B.M., M.L., W.H., M.P.F.).
Arterioscler Thromb Vasc Biol ; 43(7): 1134-1153, 2023 07.
Article in En | MEDLINE | ID: mdl-37078287
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Aneurysm / Aortic Aneurysm, Thoracic / Induced Pluripotent Stem Cells / Aortic Root Aneurysm / Marfan Syndrome Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2023 Type: Article
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Aortic Aneurysm / Aortic Aneurysm, Thoracic / Induced Pluripotent Stem Cells / Aortic Root Aneurysm / Marfan Syndrome Type of study: Prognostic_studies / Risk_factors_studies Limits: Animals Language: En Journal: Arterioscler Thromb Vasc Biol Journal subject: ANGIOLOGIA Year: 2023 Type: Article