The potential beneficial effects of <i>Lactobacillus plantarum</i> GM11 on rats with chronic unpredictable mild stress- induced depression.

Ma, Jie; Wang, Junrui; Wang, Gang; Wan, Yujun; Li, Nanzhen; Luo, Lijuan; Gou, Hongmei; Gu, Jianwen

The potential beneficial effects of Lactobacillus plantarum GM11 on rats with chronic unpredictable mild stress- induced depression.

Ma, Jie; Wang, Junrui; Wang, Gang; Wan, Yujun; Li, Nanzhen; Luo, Lijuan; Gou, Hongmei; Gu, Jianwen.

Affiliation

Ma J; Department of Research and Development, Weichuang Tianyi Biotechnology Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Wang J; Savaid Medical School, University of Chinese Academy of Sciences, Beijing, People's Republic of China.
Wang G; Department of Orthopaedics, Chengdu Second People's Hospital, Chengdu, Sichuan, People's Republic of China.
Wan Y; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Li N; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Luo L; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Gou H; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.
Gu J; Sichuan Food Fermentation Industry Research and Design Institute Co., Ltd, Chengdu, Sichuan, People's Republic of China.

Nutr Neurosci ; 27(5): 413-424, 2024 May.

Article in En | MEDLINE | ID: mdl-37116073

Subject(s)

Depression; Lactobacillus plantarum; Rats; Male; Animals; Depression/drug therapy; Depression/etiology; Depression/metabolism; Antidepressive Agents/therapeutic use; Antidepressive Agents/pharmacology; Brain-Derived Neurotrophic Factor/genetics; Brain-Derived Neurotrophic Factor/metabolism; Hypothalamo-Hypophyseal System; Rats, Sprague-Dawley; Pituitary-Adrenal System; Hippocampus/metabolism; Serotonin/metabolism; Neurotransmitter Agents/metabolism; RNA, Messenger/metabolism; Stress, Psychological/psychology; Disease Models, Animal

Key words

Hypothalamic-Pituitary-Adrenal (HPA) axis; Lactobacillus plantarum; brain-derived neurotrophic factor (BDNF); cAMP response element binding protein (CREB); chronic unpredictable mild stress; depression; probiotics; psychobiotics

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Lactobacillus plantarum / Depression Limits: Animals Language: En Journal: Nutr Neurosci Journal subject: CIENCIAS DA NUTRICAO / NEUROLOGIA Year: 2024 Type: Article

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