IMPA2 blocks cervical cancer cell apoptosis and induces paclitaxel resistance through p53-mediated AIFM2 regulation.

Xie, Kexin; Liu, Lei; Wang, Min; Li, Xianping; Wang, Bingqi; Yin, Sheng; Chen, Wanxin; Lin, Yingrui; Zhu, Xiaolin

Xie, Kexin; Liu, Lei; Wang, Min; Li, Xianping; Wang, Bingqi; Yin, Sheng; Chen, Wanxin; Lin, Yingrui; Zhu, Xiaolin.

Acta Biochim Biophys Sin (Shanghai) ; 55(4): 623-632, 2023 Apr 28.

Article in En | MEDLINE | ID: mdl-37140233

Subject(s)

Paclitaxel; Uterine Cervical Neoplasms; Female; Humans; Paclitaxel/pharmacology; Tumor Suppressor Protein p53/genetics; Tumor Suppressor Protein p53/metabolism; Uterine Cervical Neoplasms/drug therapy; Uterine Cervical Neoplasms/genetics; Uterine Cervical Neoplasms/pathology; Apoptosis/genetics; Apoptosis Regulatory Proteins/metabolism; Gene Expression Regulation, Neoplastic; Cell Line, Tumor; Mitochondrial Proteins/metabolism

Key words

apoptosis; cervical cancer; paclitaxel

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Uterine Cervical Neoplasms / Paclitaxel Type of study: Prognostic_studies Limits: Female / Humans Language: En Journal: Acta Biochim Biophys Sin (Shanghai) Journal subject: BIOFISICA / BIOQUIMICA Year: 2023 Type: Article

Fulltext

XML

PubMed Links

Search on Google