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5-ALA treatment increases intracellular heme levels and enhances CYP3A4 activity in genome-edited Caco-2 cells.
Watanabe, Keita; Negoro, Ryosuke; Fujita, Takuya.
Affiliation
  • Watanabe K; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan.
  • Negoro R; Laboratory of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan. Electronic address: negoro-r@fc.ritsumei.ac.jp.
  • Fujita T; Laboratory of Molecular Pharmacokinetics, Graduate School of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan; Laboratory of Molecular Pharmacokinetics, College of Pharmaceutical Sciences, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan; Research Center for Drug Discovery and Development, Ritsumeikan University, 1-1-1 Noji-Higashi, Kusatsu, 525-8577, Japan.
Biochem Biophys Res Commun ; 664: 94-99, 2023 07 05.
Article in En | MEDLINE | ID: mdl-37141642
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP3A / Aminolevulinic Acid Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2023 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Cytochrome P-450 CYP3A / Aminolevulinic Acid Type of study: Prognostic_studies Limits: Humans Language: En Journal: Biochem Biophys Res Commun Year: 2023 Type: Article Affiliation country: Japan