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A common mechanism of Sec61 translocon inhibition by small molecules.
Itskanov, Samuel; Wang, Laurie; Junne, Tina; Sherriff, Rumi; Xiao, Li; Blanchard, Nicolas; Shi, Wei Q; Forsyth, Craig; Hoepfner, Dominic; Spiess, Martin; Park, Eunyong.
Affiliation
  • Itskanov S; Biophysics Graduate Program, University of California, Berkeley, Berkeley, CA, USA.
  • Wang L; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
  • Junne T; Biozentrum, University of Basel, Basel, Switzerland.
  • Sherriff R; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA.
  • Xiao L; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USA.
  • Blanchard N; Université de Haute-Alsace, Université de Strasbourg, CNRS, LIMA, UMR 7042, Mulhouse, France.
  • Shi WQ; Department of Chemistry, Ball State University, Muncie, IN, USA.
  • Forsyth C; Department of Chemistry and Biochemistry, The Ohio State University, Columbus, OH, USA.
  • Hoepfner D; Novartis Institutes for BioMedical Research, Novartis Pharma AG, Forum 1 Novartis Campus, Basel, Switzerland.
  • Spiess M; Biozentrum, University of Basel, Basel, Switzerland.
  • Park E; Department of Molecular and Cell Biology, University of California, Berkeley, Berkeley, CA, USA. eunyong_park@berkeley.edu.
Nat Chem Biol ; 19(9): 1063-1071, 2023 09.
Article in En | MEDLINE | ID: mdl-37169959
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endoplasmic Reticulum / Membrane Proteins Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2023 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Endoplasmic Reticulum / Membrane Proteins Limits: Humans Language: En Journal: Nat Chem Biol Journal subject: BIOLOGIA / QUIMICA Year: 2023 Type: Article Affiliation country: United States