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Cancer-cell-derived fumarate suppresses the anti-tumor capacity of CD8+ T cells in the tumor microenvironment.
Cheng, Jie; Yan, Jinxin; Liu, Ying; Shi, Jiangzhou; Wang, Haoyu; Zhou, Hanyang; Zhou, Yinglin; Zhang, Tongcun; Zhao, Lina; Meng, Xianbin; Gong, Haipeng; Zhang, Xinxiang; Zhu, Haichuan; Jiang, Peng.
Affiliation
  • Cheng J; School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.
  • Yan J; School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.
  • Liu Y; Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
  • Shi J; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Hubei 430081, China.
  • Wang H; School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.
  • Zhou H; School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zhou Y; Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China.
  • Zhang T; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Hubei 430081, China.
  • Zhao L; School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China.
  • Meng X; National Center for Protein Science, Tsinghua University, Beijing 100084, China.
  • Gong H; School of Life Sciences, Tsinghua University, Beijing 100084, China; MOE Key Laboratory of Bioinformatics, Beijing Advanced Innovation Center for Structural Biology, School of Life Sciences, Tsinghua University, Beijing 100084, China.
  • Zhang X; Beijing National Laboratory for Molecular Sciences (BNLMS), Key Laboratory of Bioorganic Chemistry and Molecular Engineering of Ministry of Education, College of Chemistry and Molecular Engineering, Peking University, Beijing 100871, China. Electronic address: zxx@pku.edu.cn.
  • Zhu H; Institute of Biology and Medicine, College of Life and Health Sciences, Wuhan University of Science and Technology, Hubei 430081, China. Electronic address: zhuhaichuan@wust.edu.cn.
  • Jiang P; School of Life Sciences, Tsinghua University, Beijing 100084, China; Tsinghua-Peking Center for Life Sciences, Beijing 100084, China. Electronic address: pengjiang@tsinghua.edu.cn.
Cell Metab ; 35(6): 961-978.e10, 2023 06 06.
Article in En | MEDLINE | ID: mdl-37178684
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD8-Positive T-Lymphocytes / Neoplasms Limits: Humans Language: En Journal: Cell Metab Journal subject: METABOLISMO Year: 2023 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: CD8-Positive T-Lymphocytes / Neoplasms Limits: Humans Language: En Journal: Cell Metab Journal subject: METABOLISMO Year: 2023 Type: Article Affiliation country: China