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Inhibition of discoidin domain receptor (DDR)-1 with nilotinib alters CSF miRNAs and is associated with reduced inflammation and vascular fibrosis in Alzheimer's disease.
Stevenson, Max; Varghese, Rency; Hebron, Michaeline L; Liu, Xiaoguang; Ratliff, Nick; Smith, Amelia; Turner, R Scott; Moussa, Charbel.
Affiliation
  • Stevenson M; Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Building D, Room 265, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA.
  • Varghese R; Genomics and Epigenomics Shared Resource, Department of Oncology, Georgetown University Medical Center, Building D, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA.
  • Hebron ML; Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Building D, Room 265, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA.
  • Liu X; Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Building D, Room 265, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA.
  • Ratliff N; Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Building D, Room 265, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA.
  • Smith A; Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Building D, Room 265, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA.
  • Turner RS; Memory Disorders Program, Department of Neurology, Georgetown University Medical Center, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA.
  • Moussa C; Translational Neurotherapeutics Program, Laboratory for Dementia and Parkinsonism, Department of Neurology, Georgetown University Medical Center, Building D, Room 265, 4000 Reservoir Rd, NW, Washington, DC, 20057, USA. cem46@georgetown.edu.
J Neuroinflammation ; 20(1): 116, 2023 May 16.
Article in En | MEDLINE | ID: mdl-37194065
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MicroRNAs / Alzheimer Disease Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2023 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: MicroRNAs / Alzheimer Disease Type of study: Clinical_trials / Risk_factors_studies Limits: Humans Language: En Journal: J Neuroinflammation Journal subject: NEUROLOGIA Year: 2023 Type: Article Affiliation country: United States