Reemergence of Marburgvirus disease: Update on current control and prevention measures and review of the literature.
Rev Med Virol
; 33(5): e2461, 2023 09.
Article
in En
| MEDLINE
| ID: mdl-37208958
ABSTRACT
In 1967, the very first case of the Marburgvirus disease (MVD) was detected in Germany and Serbia sequentially. Since then, MVD has been considered one of the most serious and deadly infectious diseases in the world with a case-fatality rate between 23% and 90% and a substantial number of recorded deaths. Marburgvirus belongs to the family of Filoviridae (filoviruses), which causes severe viral hemorrhagic fever (VHF). Some major risk factors for human infections are close contact with African fruit bats, MVD-infected non-human primates, and MVD-infected individuals. Currently, there is no vaccine or specific treatment for MVD, which emphasizes the seriousness of this disease. In July 2022, the World Health Organization reported outbreaks of MVD in Ghana after two suspected VHF cases were detected. This was followed in February and March 2023 with the emergence of the virus in two countries new to the virus Equatorial Guinea and Tanzania, respectively. In this review, we aim to highlight the characteristics, etiology, epidemiology, and clinical symptoms of MVD, along with the current prevention measures and the possible treatments to control this virus.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Chiroptera
/
Hemorrhagic Fever, Ebola
/
Ebolavirus
/
Marburgvirus
/
Marburg Virus Disease
Type of study:
Diagnostic_studies
/
Etiology_studies
/
Risk_factors_studies
Limits:
Animals
/
Humans
Language:
En
Journal:
Rev Med Virol
Journal subject:
VIROLOGIA
Year:
2023
Type:
Article
Affiliation country:
United kingdom