Human Wharton's Jelly Mesenchymal Stem Cell Secretome Modifies the Processes of Neuroprotection and Epithelial-Mesenchymal Transition in Retinal Pigment Epithelium at Transcriptional Level.

Nowroozzadeh, M Hossein; Ghazanfari, Shiva; Sanie-Jahromi, Fatemeh

Nowroozzadeh, M Hossein; Ghazanfari, Shiva; Sanie-Jahromi, Fatemeh.

Affiliation

Nowroozzadeh MH; Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Zand Boulevard, Poostchi Street, Shiraz, Iran.
Ghazanfari S; Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Zand Boulevard, Poostchi Street, Shiraz, Iran.
Sanie-Jahromi F; Poostchi Ophthalmology Research Center, Department of Ophthalmology, School of Medicine, Shiraz University of Medical Sciences, Zand Boulevard, Poostchi Street, Shiraz, Iran. fsanie@sums.ac.ir.

Mol Biol Rep ; 50(7): 5725-5732, 2023 Jul.

Article in En | MEDLINE | ID: mdl-37217618

Subject(s)

Mesenchymal Stem Cells; Vitreoretinopathy, Proliferative; Wharton Jelly; Humans; Retinal Pigment Epithelium; Epithelial-Mesenchymal Transition/genetics; Wharton Jelly/metabolism; Brain-Derived Neurotrophic Factor/metabolism; Neuroprotection; Secretome; Vitreoretinopathy, Proliferative/drug therapy; Vitreoretinopathy, Proliferative/metabolism; Mesenchymal Stem Cells/metabolism

Key words

EMT; Human Wharton's jelly mesenchymal stem cell secretome; Neuroprotection; PVR; RPE

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Vitreoretinopathy, Proliferative / Wharton Jelly / Mesenchymal Stem Cells Limits: Humans Language: En Journal: Mol Biol Rep Year: 2023 Type: Article Affiliation country: Iran

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