Loss of MD1 Promotes Inflammatory and Apoptotic Atrial Remodelling in Diabetic Cardiomyopathy by Activating the TLR4/NF-&#954;B Signalling Pathway.

Shi, Tonghuan; Wang, Guangji; Peng, Jianye; Chen, Manhua

Loss of MD1 Promotes Inflammatory and Apoptotic Atrial Remodelling in Diabetic Cardiomyopathy by Activating the TLR4/NF-κB Signalling Pathway.

Shi, Tonghuan; Wang, Guangji; Peng, Jianye; Chen, Manhua.

Affiliation

Shi T; Department of Cardiology, Renmin Hospital of Wuhan University, Wuhan, China.
Wang G; Hubei Key Laboratory of Cardiology, Cardiovascular Research Institute of Wuhan University, Wuhan, China.
Peng J; Department of Cardiology, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.
Chen M; Key Laboratory for Molecular Diagnosis of Hubei Province, The Central Hospital of Wuhan, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, China.

Pharmacology ; 108(4): 311-320, 2023.

Article in En | MEDLINE | ID: mdl-37231994

Subject(s)

Atrial Fibrillation; Atrial Remodeling; Diabetes Mellitus, Experimental; Diabetic Cardiomyopathies; Animals; Mice; Diabetes Mellitus, Experimental/complications; Diabetes Mellitus, Experimental/chemically induced; Diabetic Cardiomyopathies/genetics; Diabetic Cardiomyopathies/metabolism; NF-kappa B/metabolism; Toll-Like Receptor 4/genetics; Toll-Like Receptor 4/metabolism

Key words

Atrial remodelling; Diabetic cardiomyopathy; Myeloid differentiation protein 1; Toll-like receptor 4

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Atrial Fibrillation / Diabetes Mellitus, Experimental / Diabetic Cardiomyopathies / Atrial Remodeling Type of study: Prognostic_studies Limits: Animals Language: En Journal: Pharmacology Year: 2023 Type: Article Affiliation country: China

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