Nesfatin-1 alleviates hyperoxia-induced lung injury in newborn mice by inhibiting oxidative stress through regulating SIRT1/PGC-1&#945; pathway.

Yang, Xiaoting; Jin, Zhan; Wang, Xi; Wu, Junmei; Yu, Wenfu; Yao, Shuihong; Zhang, Lixin; Gan, Chunchun

Nesfatin-1 alleviates hyperoxia-induced lung injury in newborn mice by inhibiting oxidative stress through regulating SIRT1/PGC-1α pathway.

Yang, Xiaoting; Jin, Zhan; Wang, Xi; Wu, Junmei; Yu, Wenfu; Yao, Shuihong; Zhang, Lixin; Gan, Chunchun.

Affiliation

Yang X; School of Medicine, Quzhou College of Technology, Jiang Yuan Road, Ke Chen District, Quzhou, Zhejiang 324000, China.
Jin Z; School of Medicine, Quzhou College of Technology, Jiang Yuan Road, Ke Chen District, Quzhou, Zhejiang 324000, China.
Wang X; Department of Urology, Quzhou People's Hospital, Min Jiang Road, Ke Chen District, Quzhou, Zhejiang 324000, China.
Wu J; Department of Burns Surgery, Quzhou Hospital of Zhejiang Medical Health Group, Wen Chang Road, Ke Chen District, Quzhou, Zhejiang 324000, China.
Yu W; School of Medicine, Quzhou College of Technology, Jiang Yuan Road, Ke Chen District, Quzhou, Zhejiang 324000, China.
Yao S; School of Medicine, Quzhou College of Technology, Jiang Yuan Road, Ke Chen District, Quzhou, Zhejiang 324000, China.
Zhang L; School of Medicine, Quzhou College of Technology, Jiang Yuan Road, Ke Chen District, Quzhou, Zhejiang 324000, China.
Gan C; School of Medicine, Quzhou College of Technology, Jiang Yuan Road, Ke Chen District, Quzhou, Zhejiang 324000, China. Electronic address: ganchunchun1990@163.com.

Cytokine ; 169: 156239, 2023 09.

Article in En | MEDLINE | ID: mdl-37301191

Subject(s)

Bronchopulmonary Dysplasia; Hyperoxia; Nucleobindins; Bronchopulmonary Dysplasia/etiology; Bronchopulmonary Dysplasia/therapy; Hyperoxia/complications; Animals; Mice; Oxidative Stress/drug effects; Rats; Nucleobindins/pharmacology; Nucleobindins/therapeutic use; Alveolar Epithelial Cells/drug effects; Alveolar Epithelial Cells/metabolism; bcl-2-Associated X Protein/metabolism; Proto-Oncogene Proteins c-bcl-2/metabolism; Superoxide Dismutase/metabolism; Sirtuin 1/genetics; Sirtuin 1/metabolism; Reactive Oxygen Species/metabolism; Malondialdehyde/metabolism; Rats, Sprague-Dawley; Male; Female

Key words

Bronchopulmonary dysplasia; Nesfatin-1; SIRT1

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Bronchopulmonary Dysplasia / Hyperoxia / Nucleobindins Type of study: Etiology_studies Limits: Animals Language: En Journal: Cytokine Journal subject: ALERGIA E IMUNOLOGIA Year: 2023 Type: Article Affiliation country: China

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