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An inducible hACE2 transgenic mouse model recapitulates SARS-CoV-2 infection and pathogenesis in vivo.
Liu, Kuo; Tang, Muxue; Xu, Wei; Meng, Xinfeng; Jin, Hengwei; Han, Maoying; Pu, Jing; Li, Yutang; Jiao, Fanke; Sun, Ruilin; Shen, Ruling; Lui, Kathy O; Lu, Lu; Zhou, Bin.
Affiliation
  • Liu K; Key Laboratory of Systems Health Science of Zhejiang Province, School of Life Science, Hangzhou Institute for Advanced Study, University of Chinese Academy of Sciences, 310024 Hangzhou, China.
  • Tang M; New Cornerstone Science Laboratory, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China.
  • Xu W; New Cornerstone Science Laboratory, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China.
  • Meng X; Key Laboratory of Medical Molecular Virology, Ministry of Education/National Health Commission/Chinese Academy of Medical Science, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microbes and Infection, Fudan
  • Jin H; New Cornerstone Science Laboratory, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China.
  • Han M; School of Life Science and Technology, ShanghaiTech University, 201210 Shanghai, China.
  • Pu J; New Cornerstone Science Laboratory, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China.
  • Li Y; New Cornerstone Science Laboratory, State Key Laboratory of Cell Biology, Shanghai Institute of Biochemistry and Cell Biology, Center for Excellence in Molecular Cell Science, University of Chinese Academy of Sciences, Chinese Academy of Sciences, 200031 Shanghai, China.
  • Jiao F; School of Life Science and Technology, ShanghaiTech University, 201210 Shanghai, China.
  • Sun R; Key Laboratory of Medical Molecular Virology, Ministry of Education/National Health Commission/Chinese Academy of Medical Science, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microbes and Infection, Fudan
  • Shen R; Key Laboratory of Medical Molecular Virology, Ministry of Education/National Health Commission/Chinese Academy of Medical Science, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microbes and Infection, Fudan
  • Lui KO; Key Laboratory of Medical Molecular Virology, Ministry of Education/National Health Commission/Chinese Academy of Medical Science, Shanghai Institute of Infectious Disease and Biosecurity, School of Basic Medical Sciences, Shanghai Frontiers Science Center of Pathogenic Microbes and Infection, Fudan
  • Lu L; Shanghai Engineering Research Center for model organizations, Shanghai Model Organisms Center, Inc., 201318 Shanghai, China.
  • Zhou B; Shanghai Laboratory Animal Research Center, 201203 Shanghai, China.
Proc Natl Acad Sci U S A ; 120(25): e2207210120, 2023 06 20.
Article in En | MEDLINE | ID: mdl-37307455
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article Affiliation country: China
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: COVID-19 Type of study: Etiology_studies Limits: Animals / Humans Language: En Journal: Proc Natl Acad Sci U S A Year: 2023 Type: Article Affiliation country: China