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Putative malignant hyperthermia mutation CaV1.1-R174W is insufficient to trigger a fulminant response to halothane or confer heat stress intolerance.
Feng, Wei; Lopez, Jose R; Antrobus, Shane; Zheng, Jing; Uryash, Arkady; Dong, Yao; Beqollari, Donald; Bannister, Roger A; Hopkins, Philip M; Beam, Kurt G; Allen, Paul D; Pessah, Isaac N.
Affiliation
  • Feng W; Department of Molecular Biosciences, University of California Davis, Davis, California, USA.
  • Lopez JR; Department of Molecular Biosciences, University of California Davis, Davis, California, USA; Department of Research, Mount Sinai Medical Center, Miami Beach, Florida, USA.
  • Antrobus S; Department of Molecular Biosciences, University of California Davis, Davis, California, USA.
  • Zheng J; Department of Molecular Biosciences, University of California Davis, Davis, California, USA.
  • Uryash A; Department of Research, Mount Sinai Medical Center, Miami Beach, Florida, USA.
  • Dong Y; Department of Molecular Biosciences, University of California Davis, Davis, California, USA.
  • Beqollari D; Department of Medicine-Cardiology Division, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Bannister RA; Department of Medicine-Cardiology Division, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Hopkins PM; Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom.
  • Beam KG; Department of Physiology and Biophysics, University of Colorado Anschutz Medical Campus, Aurora, Colorado, USA.
  • Allen PD; Department of Molecular Biosciences, University of California Davis, Davis, California, USA; Institute of Medical Research at St James's, University of Leeds, Leeds, United Kingdom.
  • Pessah IN; Department of Molecular Biosciences, University of California Davis, Davis, California, USA. Electronic address: inpessah@ucdavis.edu.
J Biol Chem ; 299(8): 104992, 2023 08.
Article in En | MEDLINE | ID: mdl-37392848
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heat-Shock Response / Large-Conductance Calcium-Activated Potassium Channel alpha Subunits / Halothane / Malignant Hyperthermia Limits: Animals Language: En Journal: J Biol Chem Year: 2023 Type: Article Affiliation country: United States
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Heat-Shock Response / Large-Conductance Calcium-Activated Potassium Channel alpha Subunits / Halothane / Malignant Hyperthermia Limits: Animals Language: En Journal: J Biol Chem Year: 2023 Type: Article Affiliation country: United States