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Deficiency of the metabolic enzyme SCHAD in pancreatic ß-cells promotes amino acid-sensitive hypoglycemia.
St-Louis, Johanna L; El Jellas, Khadija; Velasco, Kelly; Slipp, Brittany A; Hu, Jiang; Helgeland, Geir; Steine, Solrun J; De Jesus, Dario F; Kulkarni, Rohit N; Molven, Anders.
Affiliation
  • St-Louis JL; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Harvard Medical School, Boston, USA; Department of Clinical Medicine, Gade Laboratory for Pathology, University of Bergen, Bergen, Norway.
  • El Jellas K; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Harvard Medical School, Boston, USA; Department of Clinical Medicine, Gade Laboratory for Pathology, University of Bergen, Bergen, Norway.
  • Velasco K; Department of Clinical Medicine, Gade Laboratory for Pathology, University of Bergen, Bergen, Norway.
  • Slipp BA; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Harvard Medical School, Boston, USA.
  • Hu J; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Harvard Medical School, Boston, USA.
  • Helgeland G; Department of Clinical Medicine, Gade Laboratory for Pathology, University of Bergen, Bergen, Norway.
  • Steine SJ; Department of Clinical Medicine, Gade Laboratory for Pathology, University of Bergen, Bergen, Norway.
  • De Jesus DF; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Harvard Medical School, Boston, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA; Harvard Stem Cell Institute, Boston, USA.
  • Kulkarni RN; Section on Islet Cell and Regenerative Biology, Joslin Diabetes Center, Harvard Medical School, Boston, USA; Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, USA; Harvard Stem Cell Institute, Boston, USA.
  • Molven A; Department of Clinical Medicine, Gade Laboratory for Pathology, University of Bergen, Bergen, Norway; Department of Pathology, Haukeland University Hospital, Bergen, Norway; Section for Cancer Genomics, Haukeland University Hospital, Bergen, Norway. Electronic address: anders.molven@uib.no.
J Biol Chem ; 299(8): 104986, 2023 08.
Article in En | MEDLINE | ID: mdl-37392854
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Congenital Hyperinsulinism / Insulin-Secreting Cells / 3-Hydroxyacyl-CoA Dehydrogenase / Insulin Secretion / Amino Acids / Hypoglycemia Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2023 Type: Article Affiliation country: Norway
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Congenital Hyperinsulinism / Insulin-Secreting Cells / 3-Hydroxyacyl-CoA Dehydrogenase / Insulin Secretion / Amino Acids / Hypoglycemia Type of study: Diagnostic_studies / Prognostic_studies Limits: Animals Language: En Journal: J Biol Chem Year: 2023 Type: Article Affiliation country: Norway