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Fetally-encoded GDF15 and maternal GDF15 sensitivity are major determinants of nausea and vomiting in human pregnancy.
Fejzo, M; Rocha, N; Cimino, I; Lockhart, S M; Petry, C; Kay, R G; Burling, K; Barker, P; George, A L; Yasara, N; Premawardhena, A; Gong, S; Cook, E; Rainbow, K; Withers, D J; Cortessis, V; Mullin, P M; MacGibbon, K W; Jin, E; Kam, A; Campbell, A; Polasek, O; Tzoneva, G; Gribble, F M; Yeo, Gsh; Lam, Byh; Saudek, V; Hughes, I A; Ong, K K; Perry, Jrb; Sutton Cole, A; Baumgarten, M; Welsh, P; Sattar, N; Smith, Gcs; Charnock Jones, D S; Coll, A P; Meek, C L; Mettananda, S; Hayward, C; Mancuso, N; O'Rahilly, S.
Affiliation
  • Fejzo M; Department of Obstetrics and Gynaecology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
  • Rocha N; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Cimino I; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Lockhart SM; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Petry C; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Kay RG; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Burling K; Peptidomics and Proteomics Core Facility, Level 4, Wellcome-MRC Institute of Metabolic Science, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, United Kingdom.
  • Barker P; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • George AL; Core Biochemical Assay Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
  • Yasara N; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Premawardhena A; Core Biochemical Assay Laboratory, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, UK.
  • Gong S; Peptidomics and Proteomics Core Facility, Level 4, Wellcome-MRC Institute of Metabolic Science, Cambridge University Hospitals NHS Foundation Trust, Cambridge CB2 0QQ, United Kingdom.
  • Cook E; Department of Paediatrics, Faculty of Medicine, University of Kelaniya, Thalagolla Road, Ragama, 11010, Sri Lanka.
  • Rainbow K; Adolescent and Adult Thalassaemia Care Center (University Medical Unit), North Colombo Teaching Hospital, Kadawatha, Sri Lanka.
  • Withers DJ; Department of Medicine, Faculty of Medicine, University of Kelaniya, Ragama, Sri Lanka.
  • Cortessis V; Department of Obstetrics and Gynaecology, University of Cambridge, NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • Mullin PM; Centre for Trophoblast Research (CTR), Department of Physiology, Development and Neuroscience, University of Cambridge, Cambridge, UK.
  • MacGibbon KW; Department of Obstetrics and Gynaecology, University of Cambridge, NIHR Cambridge Biomedical Research Centre, Cambridge, UK.
  • Jin E; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Kam A; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Campbell A; Department of Obstetrics and Gynaecology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
  • Polasek O; Department of Population and Public Health Sciences, Keck School of Medicine, University of Southern California.
  • Tzoneva G; Department of Obstetrics and Gynaecology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
  • Gribble FM; Hyperemesis Education and Research Foundation, Clackamas, OR.
  • Yeo G; Department of Obstetrics and Gynaecology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
  • Lam B; Department of Obstetrics and Gynaecology, Keck School of Medicine, University of Southern California, Los Angeles, CA.
  • Saudek V; Centre for Genomic and Experimental Medicine, Institute of Genetics and Molecular Medicine, University of Edinburgh, Edinburgh, UK.
  • Hughes IA; Faculty of Medicine, University of Split, Split, Croatia.
  • Ong KK; Regeneron Genetics Center, Tarrytown, NY, USA.
  • Perry J; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Sutton Cole A; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Baumgarten M; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Welsh P; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Sattar N; Department of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, University of Cambridge, Cambridge, UK.
  • Smith G; Department of Paediatrics, Cambridge University Hospitals NHS Foundation Trust, University of Cambridge, Cambridge, UK.
  • Charnock Jones DS; MRC Epidemiology Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Coll AP; Medical Research Council (MRC) Metabolic Diseases Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Meek CL; MRC Epidemiology Unit, Wellcome-MRC Institute of Metabolic Science, University of Cambridge, Cambridge, UK.
  • Mettananda S; Department of Obstetrics and Gynaecology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Hayward C; Department of Obstetrics and Gynaecology, Cambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
  • Mancuso N; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
  • O'Rahilly S; School of Cardiovascular and Metabolic Health, University of Glasgow, Glasgow, UK.
bioRxiv ; 2023 Jun 04.
Article in En | MEDLINE | ID: mdl-37398065
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: Canada
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Diagnostic_studies Language: En Journal: BioRxiv Year: 2023 Type: Article Affiliation country: Canada