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Ursolic acid-rich extract presents trypanocidal action in vitro but worsens mice under experimental acute Chagas disease.
Daga, Maiara A; Nicolau, Scheila T; Jurumenha-Barreto, Juliana; Lima, Lucas B S; Cabral, Isaac L; Pivotto, Ana Paula; Stefanello, Amanda; Amorim, João P A; Hoscheid, Jaqueline; Silva, Edson A; Ayala, Thaís S; Menolli, Rafael A.
Affiliation
  • Daga MA; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Nicolau ST; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Jurumenha-Barreto J; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Lima LBS; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Cabral IL; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Pivotto AP; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Stefanello A; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Amorim JPA; Center of Biological and Health Sciences, Western Parana State University, Cascavel, Brazil.
  • Hoscheid J; Professional Master's Program in Medicinal Plants and Herbal Medicine in Primary Care, Universidade Paranaense, Umuarama, Brazil.
  • Silva EA; Laboratory of Biotechnological Processes and Separation, Center of Exact and Technological Sciences, Western Parana State University, Toledo, Brazil.
  • Ayala TS; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
  • Menolli RA; Laboratory of Applied Immunology, Center of Medical and Pharmaceutical Sciences, Western Parana State University, Cascavel, Brazil.
Parasite Immunol ; 45(10): e13005, 2023 10.
Article in En | MEDLINE | ID: mdl-37467029
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Trypanocidal Agents / Trypanosoma cruzi / Chagas Disease Limits: Animals Language: En Journal: Parasite Immunol Year: 2023 Type: Article Affiliation country: Brazil
Fulltext
Print
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Triterpenes / Trypanocidal Agents / Trypanosoma cruzi / Chagas Disease Limits: Animals Language: En Journal: Parasite Immunol Year: 2023 Type: Article Affiliation country: Brazil