MicroRNA-577/EIF5A2 axis suppressed the proliferation of DDP-resistant nasopharyngeal carcinoma cells by blocking TGF-ß signaling pathway.

Wu, Renrui; Zhong, Qiong; Liu, Huafeng; Liu, Shubin

Wu, Renrui; Zhong, Qiong; Liu, Huafeng; Liu, Shubin.

Affiliation

Wu R; Department of Oncology, Ganzhou City People's Hospital, Ganzhou, China.
Zhong Q; Department of Oncology, Ganzhou City People's Hospital, Ganzhou, China.
Liu H; Department of Oncology, Ganzhou City People's Hospital, Ganzhou, China.
Liu S; Department of Oncology, Ganzhou City People's Hospital, Ganzhou, China.

Chem Biol Drug Des ; 102(4): 815-827, 2023 10.

Article in En | MEDLINE | ID: mdl-37500510

Subject(s)

MicroRNAs; Nasopharyngeal Neoplasms; Animals; Mice; Cell Line, Tumor; Cell Movement; Cell Proliferation; Epithelial-Mesenchymal Transition; Gene Expression Regulation, Neoplastic; MicroRNAs/genetics; Nasopharyngeal Carcinoma/drug therapy; Nasopharyngeal Carcinoma/genetics; Nasopharyngeal Neoplasms/drug therapy; Nasopharyngeal Neoplasms/genetics; Nasopharyngeal Neoplasms/metabolism; Signal Transduction; Transforming Growth Factor beta/genetics; Drug Resistance, Neoplasm/genetics; Eukaryotic Translation Initiation Factor 5A

Key words

TGF-ß signaling pathway; eukaryotic translation initiation factor 5A2; microRNA-577; nasopharyngeal carcinoma

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Nasopharyngeal Neoplasms / MicroRNAs Limits: Animals Language: En Journal: Chem Biol Drug Des Journal subject: BIOQUIMICA / FARMACIA / FARMACOLOGIA Year: 2023 Type: Article Affiliation country: China

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