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Ocular instillation of conditioned medium from mesenchymal stem cells is effective for dry eye syndrome by improving corneal barrier function.
Imaizumi, Tsutomu; Hayashi, Ryuhei; Kudo, Yuji; Li, Xiaoqin; Yamaguchi, Kaito; Shibata, Shun; Okubo, Toru; Ishii, Tsuyoshi; Honma, Yoichi; Nishida, Kohji.
Affiliation
  • Imaizumi T; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.
  • Hayashi R; Basic Research Development Division, ROHTO Pharmaceutical, Ikuno-ku, Osaka, 544-8666, Japan.
  • Kudo Y; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan. ryuhei.hayashi@ophthal.med.osaka-u.ac.jp.
  • Li X; Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan. ryuhei.hayashi@ophthal.med.osaka-u.ac.jp.
  • Yamaguchi K; Institute for Open and Transdisciplinary Research Initiatives, Osaka University, Osaka, Osaka, 565-0871, Japan. ryuhei.hayashi@ophthal.med.osaka-u.ac.jp.
  • Shibata S; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.
  • Okubo T; Basic Research Development Division, ROHTO Pharmaceutical, Ikuno-ku, Osaka, 544-8666, Japan.
  • Ishii T; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.
  • Honma Y; Department of Ophthalmology, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.
  • Nishida K; Department of Stem Cells and Applied Medicine, Osaka University Graduate School of Medicine, Suita, Osaka, 565-0871, Japan.
Sci Rep ; 13(1): 13100, 2023 08 11.
Article in En | MEDLINE | ID: mdl-37567940
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dry Eye Syndromes / Mesenchymal Stem Cells / Corneal Injuries Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2023 Type: Article Affiliation country: Japan
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Dry Eye Syndromes / Mesenchymal Stem Cells / Corneal Injuries Type of study: Prognostic_studies Limits: Animals / Humans Language: En Journal: Sci Rep Year: 2023 Type: Article Affiliation country: Japan