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Effect of lemborexant on pharmacokinetics of clozapine: A potential drug-drug interaction mediated by time-dependent inhibition of CYP3A4.
Watanabe, Kenya; Misaka, Shingen; Kanno-Nozaki, Keiko; Chiyoda, Takaaki; Suzuki, Yuhei; Sato, Akiko; Suto, Takahiro; Kuroda, Junko; Shimomura, Kenju; Miura, Itaru; Yabe, Hirooki.
Affiliation
  • Watanabe K; Department of Pharmacy, Fukushima Medical University Hospital, Fukushima, Japan.
  • Misaka S; Department of Pharmacy, Fukushima Medical University Hospital, Fukushima, Japan.
  • Kanno-Nozaki K; Department of Bioregulation and Pharmacological Medicine, School of Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
  • Chiyoda T; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
  • Suzuki Y; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
  • Sato A; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
  • Suto T; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
  • Kuroda J; Department of Pharmacy, Fukushima Medical University Hospital, Fukushima, Japan.
  • Shimomura K; Department of Pharmacy, Fukushima Medical University Hospital, Fukushima, Japan.
  • Miura I; Department of Bioregulation and Pharmacological Medicine, School of Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
  • Yabe H; Department of Neuropsychiatry, School of Medicine, Fukushima Medical University School of Medicine, Fukushima, Japan.
Br J Clin Pharmacol ; 90(1): 354-359, 2024 01.
Article in En | MEDLINE | ID: mdl-37596710
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antipsychotic Agents / Clozapine Limits: Adult / Humans / Male Language: En Journal: Br J Clin Pharmacol Year: 2024 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Antipsychotic Agents / Clozapine Limits: Adult / Humans / Male Language: En Journal: Br J Clin Pharmacol Year: 2024 Type: Article Affiliation country: Japan