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Tolerogenic dendritic cells: promising cell therapy for acute kidney injury.
Nakamura, Yasuna; Inoue, Tsuyoshi.
Affiliation
  • Nakamura Y; Department of Physiology of Visceral Function and Body Fluid, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan.
  • Inoue T; Department of Physiology of Visceral Function and Body Fluid, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. Electronic address: ts-inoue@nagasaki-u.ac.jp.
Kidney Int ; 104(3): 420-422, 2023 09.
Article in En | MEDLINE | ID: mdl-37599014
ABSTRACT
There is still no established treatment for acute kidney injury (AKI), and the intervention of AKI remains limited to supportive treatments. Li et al. demonstrated the mechanism by which immune tolerance by dendritic cell ameliorates AKI in a mouse ischemia-reperfusion injury model. The phase I/II clinical trials of tolerogenic dendritic cell therapy have been conducted for kidney transplantation, so it is expected to have potential as a cell therapy for AKI in the future.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kidney Transplantation / Acute Kidney Injury Limits: Animals Language: En Journal: Kidney Int Year: 2023 Type: Article Affiliation country: Japan
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Kidney Transplantation / Acute Kidney Injury Limits: Animals Language: En Journal: Kidney Int Year: 2023 Type: Article Affiliation country: Japan