Patient-Derived Ex Vivo Cultures and Endpoint Assays with Surrogate Biomarkers in Functional Testing for Prediction of Therapeutic Response.

Tsukamoto, Yoshiyuki; Hirashita, Yuka; Shibata, Tomotaka; Fumoto, Shoichi; Kurogi, Shusaku; Nakada, Chisato; Kinoshita, Keisuke; Fuchino, Takafumi; Murakami, Kazunari; Inomata, Masafumi; Moriyama, Masatsugu; Hijiya, Naoki

Tsukamoto, Yoshiyuki; Hirashita, Yuka; Shibata, Tomotaka; Fumoto, Shoichi; Kurogi, Shusaku; Nakada, Chisato; Kinoshita, Keisuke; Fuchino, Takafumi; Murakami, Kazunari; Inomata, Masafumi; Moriyama, Masatsugu; Hijiya, Naoki.

Affiliation

Tsukamoto Y; Department of Molecular Pathology, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Hirashita Y; Department of Molecular Pathology, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Shibata T; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
Fumoto S; Department of Gastroenterological and Pediatric Surgery, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
Kurogi S; Department of Surgery, Oita Nakamura Hospital, Oita 879-5593, Japan.
Nakada C; Department of Molecular Pathology, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Kinoshita K; Department of Urology, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
Fuchino T; Department of Molecular Pathology, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Murakami K; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
Inomata M; Department of Molecular Pathology, Faculty of Medicine, Oita University, 1-1 Hasama-machi, Oita 879-5593, Japan.
Moriyama M; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita 879-5593, Japan.
Hijiya N; Department of Gastroenterology, Faculty of Medicine, Oita University, Oita 879-5593, Japan.

Cancers (Basel) ; 15(16)2023 Aug 15.

Article in En | MEDLINE | ID: mdl-37627132

Key words

3-(4,5-Dimethylthiazol-2-yl)-2,5-diphenyltetrazolium bromide (MTT); collagen droplet-embedded culture drug sensitivity test (CD-DST); extracellular matrix (ECM); functional testing; lactate dehydrogenase (LDH); micro-organospheres (MOSs); organs on chips; patient derived cancer organoids (PDCOs); patient derived explants (PDEs); spheroid

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Full text: 1 Collection: 01-internacional Database: MEDLINE Type of study: Prognostic_studies / Risk_factors_studies Language: En Journal: Cancers (Basel) Year: 2023 Type: Article Affiliation country: Japan

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