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Structure of the thrombopoietin-MPL receptor complex is a blueprint for biasing hematopoiesis.
Tsutsumi, Naotaka; Masoumi, Zahra; James, Sophie C; Tucker, Julie A; Winkelmann, Hauke; Grey, William; Picton, Lora K; Moss, Lucie; Wilson, Steven C; Caveney, Nathanael A; Jude, Kevin M; Gati, Cornelius; Piehler, Jacob; Hitchcock, Ian S; Garcia, K Christopher.
Affiliation
  • Tsutsumi N; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 9
  • Masoumi Z; York Biomedical Research Institute, Department of Biology, University of York, Heslington, York YO10 5DD, UK.
  • James SC; York Biomedical Research Institute, Department of Biology, University of York, Heslington, York YO10 5DD, UK.
  • Tucker JA; York Biomedical Research Institute, Department of Biology, University of York, Heslington, York YO10 5DD, UK.
  • Winkelmann H; Department of Biology/Chemistry and Center of Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany.
  • Grey W; York Biomedical Research Institute, Department of Biology, University of York, Heslington, York YO10 5DD, UK.
  • Picton LK; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Moss L; York Biomedical Research Institute, Department of Biology, University of York, Heslington, York YO10 5DD, UK.
  • Wilson SC; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Caveney NA; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA.
  • Jude KM; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 9
  • Gati C; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Biosciences Division, SLAC National Accelerator Laboratory, Menlo Park, CA 94025, USA.
  • Piehler J; Department of Biology/Chemistry and Center of Cellular Nanoanalytics, Osnabrück University, 49076 Osnabrück, Germany.
  • Hitchcock IS; York Biomedical Research Institute, Department of Biology, University of York, Heslington, York YO10 5DD, UK. Electronic address: ian.hitchcock@york.ac.uk.
  • Garcia KC; Department of Molecular and Cellular Physiology, Stanford University School of Medicine, Stanford, CA 94305, USA; Department of Structural Biology, Stanford University School of Medicine, Stanford, CA 94305, USA; Howard Hughes Medical Institute, Stanford University School of Medicine, Stanford, CA 9
Cell ; 186(19): 4189-4203.e22, 2023 09 14.
Article in En | MEDLINE | ID: mdl-37633268
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombopoietin / Receptors, Thrombopoietin Limits: Animals / Humans Language: En Journal: Cell Year: 2023 Type: Article
Fulltext
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Thrombopoietin / Receptors, Thrombopoietin Limits: Animals / Humans Language: En Journal: Cell Year: 2023 Type: Article