[Genome sequence analysis of two SARS-CoV-2 virus infections in Inner Mongolia, 2022].
Zhonghua Yu Fang Yi Xue Za Zhi
; 57(10): 1630-1634, 2023 Oct 06.
Article
in Zh
| MEDLINE
| ID: mdl-37859382
ABSTRACT
The target gene sequences of the novel coronaviruses obtained by sequencing were compared with the reference sequences to analyze the genetic variation of the two cases of the novel coronaviruses from Inner Mongolia Autonomous Region in 2022 and to explore the sources of infection. The results showed that the two sequences belonged to different evolutionary branches, Delta (AY.122) and Omicron (BA.1.1), respectively. hCoV-19/Inner Mongolia/IVDC-591/2022 had 48 single nucleotide polymorphisms on the genome sequences, sharing 40 nucleotide mutation sites with a Mongolian strain; hCoV-19/Inner Mongolia/IVDC-592/2022 genome shared 57 nucleotide mutation sites with a UK strain, and the nucleotide mutation site identity was 100% (57/57). Phylogenetic analysis showed that the target gene sequences were not directly related to domestic novel coronavirus sequences during the same period, but were related to isolates from Europe and Mongolia.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
COVID-19
Limits:
Humans
Language:
Zh
Journal:
Zhonghua Yu Fang Yi Xue Za Zhi
Year:
2023
Type:
Article
Affiliation country:
China