Effect of next-step antidepressant treatment on suicidal ideation: findings from the VAST-D trial.

Zisook, Sidney; Moutier, Christine Yu; Rush, A John; Johnson, Gary R; Tal, Ilanit; Chen, P J; Davis, Lori L; Hicks, Paul B; Wilcox, James; Planeta, Beata; Lauro, Kimberly Weingart; Scrymgeour, Alexandra A; Kasckow, John; Mohamed, Somaia

Zisook, Sidney; Moutier, Christine Yu; Rush, A John; Johnson, Gary R; Tal, Ilanit; Chen, P J; Davis, Lori L; Hicks, Paul B; Wilcox, James; Planeta, Beata; Lauro, Kimberly Weingart; Scrymgeour, Alexandra A; Kasckow, John; Mohamed, Somaia.

Affiliation

Zisook S; University of California San Diego, San Diego, CA, USA.
Moutier CY; VA San Diego Healthcare System, San Diego, CA, USA.
Rush AJ; American Foundation for Suicide Prevention, New York, NY, USA.
Johnson GR; Duke Medical School, Durham, NC, USA.
Tal I; Duke-National University of Singapore, Singapore.
Chen PJ; Cooperative Studies Program Coordinating Center, VA Connecticut Healthcare System, West Haven, CT, USA.
Davis LL; VA San Diego Healthcare System, San Diego, CA, USA.
Hicks PB; Department of Psychiatry, VA Northeast Ohio Healthcare System, and Case Western Reserve University School of Medicine, Cleveland, OH, USA.
Wilcox J; Tuscaloosa VA Medical Center, Tuscaloosa, AL, USA.
Planeta B; Department of Psychiatry, Texas A&M College of Medicine, Temple, TX, USA.
Lauro KW; Department of Veterans Affairs, Phoenix, AZ, USA.
Scrymgeour AA; Cooperative Studies Program Coordinating Center, VA Connecticut Healthcare System, West Haven, CT, USA.
Kasckow J; VA San Diego Healthcare System, San Diego, CA, USA.
Mohamed S; Cooperative Studies Program Clinical Research Pharmacy Coordinating Center, Albuquerque, NM, USA.

Psychol Med ; 54(6): 1172-1183, 2024 Apr.

Article in En | MEDLINE | ID: mdl-37859623

Subject(s)

Depressive Disorder, Major; Suicidal Ideation; Humans; Male; Female; Bupropion/therapeutic use; Depressive Disorder, Major/epidemiology; Antidepressive Agents/therapeutic use; Aripiprazole/pharmacology; Aripiprazole/therapeutic use

Key words

VA Augmentation and Swritching Treatments for Depression (VAST-D) study; antidepressant medications; difficult to treat depression; major depressive disorder; next-step treatments; safety; suicidal ideation; suicidal thoughts and behaviors; suicide; suicide risk; treatment emergent suicidality; treatment resistant depression

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Depressive Disorder, Major / Suicidal Ideation Limits: Female / Humans / Male Language: En Journal: Psychol Med Year: 2024 Type: Article Affiliation country: United States

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