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Comparison of two lab-scale protocols for enhanced mRNA-based CAR-T cell generation and functionality.
von Auw, Nadine; Serfling, Robert; Kitte, Reni; Hilger, Nadja; Zhang, Chengkang; Gebhardt, Clara; Duenkel, Anna; Franz, Paul; Koehl, Ulrike; Fricke, Stephan; Tretbar, U Sandy.
Affiliation
  • von Auw N; Department for Cell and Gene Therapy Development, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Serfling R; Department for Cell and Gene Therapy Development, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Kitte R; Department for Cell and Gene Therapy Development, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Hilger N; Department for Cell and Gene Therapy Development, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Zhang C; Lonza, 9900 Medical Center Drive, Rockville, MD, 20850, USA.
  • Gebhardt C; Department for Cell and Gene Therapy Development, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Duenkel A; Department for Cell and Gene Therapy Development, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Franz P; Department for Cell and Gene Therapy Development, Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Koehl U; Fraunhofer Cluster of Excellence Immune-Mediated Diseases CIMD, Leipzig, Germany.
  • Fricke S; Fraunhofer Institute for Cell Therapy and Immunology (IZI), Perlickstr. 1, 04103, Leipzig, Germany.
  • Tretbar US; Medical Faculty, Institute for Clinical Immunology, University of Leipzig, Johannisallee 30, 04103, Leipzig, Germany.
Sci Rep ; 13(1): 18160, 2023 10 24.
Article in En | MEDLINE | ID: mdl-37875523

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Receptors, Chimeric Antigen Language: En Journal: Sci Rep Year: 2023 Type: Article Affiliation country: Germany

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: T-Lymphocytes / Receptors, Chimeric Antigen Language: En Journal: Sci Rep Year: 2023 Type: Article Affiliation country: Germany