Activation of Chaperone-Mediated Autophagy Inhibits the Aryl Hydrocarbon Receptor Function by Degrading This Receptor in Human Lung Epithelial Carcinoma A549 Cells.

Xiong, Rui; Shao, Dan; Do, Sandra; Chan, William K

Xiong, Rui; Shao, Dan; Do, Sandra; Chan, William K.

Affiliation

Xiong R; Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA.
Shao D; Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA.
Do S; Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA.
Chan WK; Department of Pharmaceutics & Medicinal Chemistry, Thomas J. Long School of Pharmacy, University of the Pacific, Stockton, CA 95211, USA.

Int J Mol Sci ; 24(20)2023 Oct 12.

Article in En | MEDLINE | ID: mdl-37894798

Subject(s)

Carcinoma; Chaperone-Mediated Autophagy; Lung Neoplasms; Humans; A549 Cells; Autophagy/genetics; Chloroquine/pharmacology; Ligands; Lung/pathology; Lung Neoplasms/metabolism; Receptors, Aryl Hydrocarbon/genetics; Receptors, Aryl Hydrocarbon/metabolism

Key words

6-AN; A549; CQ; LAMP2; aryl hydrocarbon receptor; chaperone-mediated autophagy

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Carcinoma / Chaperone-Mediated Autophagy / Lung Neoplasms Limits: Humans Language: En Journal: Int J Mol Sci Year: 2023 Type: Article Affiliation country: United States

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