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Targeted Reversible Covalent Modification of a Noncatalytic Lysine of the Krev Interaction Trapped 1 Protein Enables Site-Directed Screening for Protein-Protein Interaction Inhibitors.
Francisco, Karol R; Bruystens, Jessica; Varricchio, Carmine; McCurdy, Sara; Wu, Jian; Lopez-Ramirez, Miguel A; Ginsberg, Mark; Caffrey, Conor R; Brancale, Andrea; Gingras, Alexandre R; Hixon, Mark S; Ballatore, Carlo.
Affiliation
  • Francisco KR; Department of Chemistry and Biochemistry, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
  • Bruystens J; Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
  • Varricchio C; Department of Pharmacology, University of California, San Diego, California 92161, United States.
  • McCurdy S; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF103NB, U.K.
  • Wu J; Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
  • Lopez-Ramirez MA; Department of Pharmacology, University of California, San Diego, California 92161, United States.
  • Ginsberg M; Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
  • Caffrey CR; Department of Pharmacology, University of California, San Diego, California 92161, United States.
  • Brancale A; Department of Medicine, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
  • Gingras AR; Center for Discovery and Innovation in Parasitic Diseases, Skaggs School of Pharmacy and Pharmaceutical Sciences, University of California, San Diego, 9500 Gilman Drive, La Jolla, California 92093, United States.
  • Hixon MS; School of Pharmacy and Pharmaceutical Sciences, Cardiff University, Cardiff CF103NB, U.K.
  • Ballatore C; Vysoká Sk̆ola Chemicko-Technologická v Praze, Department of Organic ChemistryTechnická 5, Prague 16628, Czech Republic.
ACS Pharmacol Transl Sci ; 6(11): 1651-1658, 2023 Nov 10.
Article in En | MEDLINE | ID: mdl-37974623
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Pharmacol Transl Sci Year: 2023 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: ACS Pharmacol Transl Sci Year: 2023 Type: Article Affiliation country: United States