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Porin-independent accumulation in Pseudomonas enables antibiotic discovery.
Geddes, Emily J; Gugger, Morgan K; Garcia, Alfredo; Chavez, Martin Garcia; Lee, Myung Ryul; Perlmutter, Sarah J; Bieniossek, Christoph; Guasch, Laura; Hergenrother, Paul J.
Affiliation
  • Geddes EJ; Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL, USA.
  • Gugger MK; Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL, USA.
  • Garcia A; Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL, USA.
  • Chavez MG; Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL, USA.
  • Lee MR; Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL, USA.
  • Perlmutter SJ; Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL, USA.
  • Bieniossek C; Roche Pharma Research and Early Development, Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Guasch L; Roche Pharma Research and Early Development, Innovation Center Basel, F. Hoffmann-La Roche Ltd, Basel, Switzerland.
  • Hergenrother PJ; Department of Chemistry and Carl R. Woese Institute for Genomic Biology, University of Illinois, Urbana, IL, USA. hergenro@illinois.edu.
Nature ; 624(7990): 145-153, 2023 Dec.
Article in En | MEDLINE | ID: mdl-37993720
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Drug Design / Porins / Anti-Bacterial Agents Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: United States
Fulltext
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PubMed Links
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Pseudomonas aeruginosa / Drug Design / Porins / Anti-Bacterial Agents Language: En Journal: Nature Year: 2023 Type: Article Affiliation country: United States