Paediatric pustulotic arthro-osteitis patient with an IL36RN variant, heterozygous c.115+6T>C, who was successfully treated with tonsillectomy: A case report and literature review.

Takami, Kenji; Tsuji, Shigeyoshi; Jokoji, Ryu; Okubo, Yukari; Higashiyama, Mari

Takami, Kenji; Tsuji, Shigeyoshi; Jokoji, Ryu; Okubo, Yukari; Higashiyama, Mari.

Affiliation

Takami K; Department of Orthopaedic Surgery, Nippon Life Hospital, Osaka, Japan.
Tsuji S; Department of Rehabilitation, Nippon Life Hospital, Osaka, Japan.
Jokoji R; Department of Psoriasis Center, Nippon Life Hospital, Osaka, Japan.
Okubo Y; Department of Pathology, Nippon Life Hospital, Osaka, Japan.
Higashiyama M; Department of Dermatology, Tokyo Medical University, Tokyo, Japan.

Exp Dermatol ; 33(1): e15016, 2024 Jan.

Article in En | MEDLINE | ID: mdl-38284206

ABSTRACT

ABSTRACT

Pustulotic arthro-osteitis (PAO) is an infrequent condition, with its manifestation in children being even rare. Some reports propose an association between genetic variants and the onset of PAO. Currently, no definitive treatment protocol exists for paediatric patients with PAO. In this study, we present the paediatric case of PAO with an IL36RN variant who was successfully treated with tonsillectomy.

Subject(s)

Osteitis; Psoriasis; Tonsillectomy; Humans; Child; Osteitis/etiology; Tonsillectomy/adverse effects; Psoriasis/complications; Interleukins

Key words

IL36RN variant; case report; paediatric-onset; pustulotic arthro-osteitis; tonsillectomy

Fulltext

XML

PubMed Links

Search on Google

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Osteitis / Psoriasis / Tonsillectomy Type of study: Etiology_studies / Guideline Limits: Child / Humans Language: En Journal: Exp Dermatol Journal subject: DERMATOLOGIA Year: 2024 Type: Article Affiliation country: Japan

Fulltext

XML

PubMed Links

Search on Google