Cognitive behavioral therapy for managing depressive and anxiety symptoms after brain injury: a meta-analysis.
Brain Inj
; 38(3): 227-240, 2024 02 23.
Article
in En
| MEDLINE
| ID: mdl-38318855
ABSTRACT
BACKGROUND:
Individuals with traumatic brain injury (TBI) are at increased risk of depression and anxiety, leading to impaired recovery. While cognitive-behavioral therapy (CBT) addresses anxiety and depression maintenance factors, its efficacy among those with TBI has not been clearly demonstrated. This review aims to bridge this gap in the literature.METHODS:
Several databases, including Medline, PsycInfo and EMBASE, were used to identify studies published between 1990 and 2021. Studies were included if (1) trials were randomized controlled trials (RCT) involving CBT-based intervention targeting anxiety and/or depression; (2) participants experienced brain injury at least 3-months previous; (3) participants were ≥18 years old. An SMD ± SE, 95% CI and heterogeneity were calculated for each outcome.RESULTS:
Thirteen RCTs were included in this meta-analysis. The pooled-sample analyses suggest that CBT interventions had small immediate post-treatment effects on reducing depression (SMD ± SE 0.391 ± 0.126, p < 0.005) and anxiety (SMD ± SE 0.247 ± 0.081, p < 0.005). Effects were sustained at a 3-months follow-up for depression. A larger effect for CBT was seen when compared with supportive therapy than control. Another sub-analysis found that individualized CBT resulted in a slightly higher effect compared to group-based CBT.CONCLUSION:
This meta-analysis provides substantial evidence for CBT in managing anxiety and depression post-TBI.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Brain Injuries
/
Cognitive Behavioral Therapy
Type of study:
Clinical_trials
/
Diagnostic_studies
/
Prognostic_studies
/
Systematic_reviews
Limits:
Adolescent
/
Adult
/
Humans
Language:
En
Journal:
Brain Inj
Journal subject:
CEREBRO
Year:
2024
Type:
Article
Affiliation country:
Canada