Spinal astroblastoma, MN1 altered in 3-year-old child: An uncommon tumor at an unusual site.
Neuropathology
; 44(4): 314-318, 2024 Aug.
Article
in En
| MEDLINE
| ID: mdl-38409890
ABSTRACT
Astroblastoma is an uncommon circumscribed glial tumor mostly involving the cerebral hemisphere. The characteristic molecular alteration is meningioma (disrupted in balanced translocation) 1 (MN1) rearrangement. No definite World Health Organization grade has been assigned as both low- and high-grade tumors are known to occur. Tumors in the spine are extremely rare; to date only three cases have been reported in the literature. A vigilant microscopy and ancillary testing aid in diagnosis when the tumors present in unusual locations, as in our case. The prompt differentiation of this tumor from its mimickers is a mandate as modalities of management are different and not clearly established.
Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Neoplasms, Neuroepithelial
Limits:
Child, preschool
/
Female
/
Humans
/
Male
Language:
En
Journal:
Neuropathology
Journal subject:
NEUROLOGIA
/
PATOLOGIA
Year:
2024
Type:
Article
Affiliation country:
India