Beneficial Effects of Fibroblast Growth Factor-1 on Retinal Pigment Epithelial Cells Exposed to High Glucose-Induced Damage: Alleviation of Oxidative Stress, Endoplasmic Reticulum Stress, and Enhancement of Autophagy.

Huang, Hsin-Wei; Yang, Chung-May; Yang, Chang-Hao

Huang, Hsin-Wei; Yang, Chung-May; Yang, Chang-Hao.

Affiliation

Huang HW; Department of Ophthalmology, Wan Fang Hospital, Taipei Medical University, No. 111, Section 3, Xinglong Road, Taipei 11696, Taiwan.
Yang CM; Graduate Institute of Clinical Medicine, College of Medicine, National Taiwan University, No. 1, Jen Ai Road Section 1, Taipei 100, Taiwan.
Yang CH; Department of Ophthalmology, National Taiwan University Hospital, No. 7, Zhongshan South Road, Taipei 100, Taiwan.

Int J Mol Sci ; 25(6)2024 Mar 11.

Article in En | MEDLINE | ID: mdl-38542166

Subject(s)

Diabetic Retinopathy; Fibroblast Growth Factor 1; Humans; Fibroblast Growth Factor 1/pharmacology; Fibroblast Growth Factor 1/metabolism; Protein Carbonylation; Retinal Pigment Epithelium/metabolism; Oxidative Stress; Apoptosis; Endoplasmic Reticulum Stress; Autophagy; Diabetic Retinopathy/metabolism; Glucose/toxicity; Glucose/metabolism; Epithelial Cells/metabolism; Retinal Pigments/metabolism

Key words

adenosine monophosphate-activated protein kinase; autophagy; diabetic retinopathy; endoplasmic reticulum stress; fibroblast growth factor-1; mammalian target of rapamycin; oxidative stress

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Fibroblast Growth Factor 1 / Diabetic Retinopathy Limits: Humans Language: En Journal: Int J Mol Sci Year: 2024 Type: Article Affiliation country: Taiwan

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