Insights into incipient oral squamous cell carcinoma: a comprehensive south-american study.
Med Oral Patol Oral Cir Bucal
; 29(4): e575-e583, 2024 Jul 01.
Article
in En
| MEDLINE
| ID: mdl-38794942
ABSTRACT
BACKGROUND:
To describe demographic and clinicopathological aspects of a South-American cohort of incipient oral squamous cell carcinoma patients. MATERIAL ANDMETHODS:
A cross-sectional, observational study was performed to assess demographic and clinicopathological characteristics of incipient oral squamous cell carcinoma patients from 6 South-American institutions.RESULTS:
One hundred and seven patients within the histopathological spectrum of incipient oral squamous cell carcinoma (in-situ and microinvasive) were included. Fifty-eight (54.2%) patients were men with a mean age of 60.69 years. Forty-nine (45.8%) and thirty-nine (36.5%) patients had history of tobacco and alcohol use, respectively. Clinically, most of the lesions were plaques (82.2%), ≥ 2 cm in extension (72%), affecting the lateral border of the tongue (55.1%), and soft palate (12.1%) with a mixed (white and red) appearance. Eighty-two (76.7%) lesions were predominantly white and 25 (23.3%) predominantly red.CONCLUSIONS:
To the best of our knowledge, this is the largest cohort of incipient oral squamous cell carcinoma patients, which raises awareness of clinicians' inspection acuteness by demonstrating the most frequent clinical aspects of this disease, potentially improving oral cancer secondary prevention strategies.
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Mouth Neoplasms
/
Carcinoma, Squamous Cell
Limits:
Adult
/
Aged
/
Aged80
/
Female
/
Humans
/
Male
/
Middle aged
Country/Region as subject:
America do sul
Language:
En
Journal:
Med Oral Patol Oral Cir Bucal
/
Med. oral patol. oral cir. bucal (Ed.impr.)
/
Medicina oral, patologiÌua oral y cirugiÌua bucal
Journal subject:
ODONTOLOGIA
Year:
2024
Type:
Article
Affiliation country:
Brazil