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Revolutionizing GPCR-ligand predictions: DeepGPCR with experimental validation for high-precision drug discovery.
Zhang, Haiping; Fan, Hongjie; Wang, Jixia; Hou, Tao; Saravanan, Konda Mani; Xia, Wei; Kan, Hei Wun; Li, Junxin; Zhang, John Z H; Liang, Xinmiao; Chen, Yang.
Affiliation
  • Zhang H; Faculty of Synthetic Biology and Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, No. 1068 Xueyuan Boulevard, Nanshan District, Shenzhen 518055, Guangdong Province, China.
  • Fan H; Ganjiang Chinese Medicine Innovation Center, Xinqizhou East Road 888, Ganjiang New Area, Nanchang 330000, China.
  • Wang J; Ganjiang Chinese Medicine Innovation Center, Xinqizhou East Road 888, Ganjiang New Area, Nanchang 330000, China.
  • Hou T; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, No. 457 Zhongshan Road, Dalian 116023, China.
  • Saravanan KM; Ganjiang Chinese Medicine Innovation Center, Xinqizhou East Road 888, Ganjiang New Area, Nanchang 330000, China.
  • Xia W; CAS Key Laboratory of Separation Science for Analytical Chemistry, Dalian Institute of Chemical Physics, Chinese Academy of Sciences, No. 457 Zhongshan Road, Dalian 116023, China.
  • Kan HW; Department of Biotechnology, Bharath Institute of Higher Education and Research, Agharam Road 173, Selaiyur, Chennai, Tamil Nadu 600073, India.
  • Li J; Faculty of Synthetic Biology and Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, No. 1068 Xueyuan Boulevard, Nanshan District, Shenzhen 518055, Guangdong Province, China.
  • Zhang JZH; Faculty of Synthetic Biology and Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, No. 1068 Xueyuan Boulevard, Nanshan District, Shenzhen 518055, Guangdong Province, China.
  • Liang X; Shenzhen Laboratory of Human Antibody Engineering, Institute of Biomedicine and Biotechnology, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, No. 1068 Xueyuan Boulevard, Nanshan District, Shenzhen 518055, Guangdong Province, China.
  • Chen Y; Faculty of Synthetic Biology and Institute of Synthetic Biology, Shenzhen Institute of Advanced Technology, Chinese Academy of Sciences, No. 1068 Xueyuan Boulevard, Nanshan District, Shenzhen 518055, Guangdong Province, China.
Brief Bioinform ; 25(4)2024 May 23.
Article in En | MEDLINE | ID: mdl-38864340

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, G-Protein-Coupled / Drug Discovery Limits: Humans Language: En Journal: Brief Bioinform Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2024 Type: Article Affiliation country: China

Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Receptors, G-Protein-Coupled / Drug Discovery Limits: Humans Language: En Journal: Brief Bioinform Journal subject: BIOLOGIA / INFORMATICA MEDICA Year: 2024 Type: Article Affiliation country: China