[Risk factors for bronchopulmonary dysplasia in twin preterm infants: a multicenter study]. / åèæ©äº§å¿æ¯æ°ç®¡èºåè²ä¸è¯å±é©å ç´ åæï¼ä¸é¡¹å¤ä¸å¿ç 究.
Zhongguo Dang Dai Er Ke Za Zhi
; 26(6): 611-618, 2024 Jun 15.
Article
in Zh
| MEDLINE
| ID: mdl-38926378
ABSTRACT
OBJECTIVES:
To investigate the risk factors for bronchopulmonary dysplasia (BPD) in twin preterm infants with a gestational age of <34 weeks, and to provide a basis for early identification of BPD in twin preterm infants in clinical practice.METHODS:
A retrospective analysis was performed for the twin preterm infants with a gestational age of <34 weeks who were admitted to 22 hospitals nationwide from January 2018 to December 2020. According to their conditions, they were divided into group A (both twins had BPD), group B (only one twin had BPD), and group C (neither twin had BPD). The risk factors for BPD in twin preterm infants were analyzed. Further analysis was conducted on group B to investigate the postnatal risk factors for BPD within twins.RESULTS:
A total of 904 pairs of twins with a gestational age of <34 weeks were included in this study. The multivariate logistic regression analysis showed that compared with group C, birth weight discordance of >25% between the twins was an independent risk factor for BPD in one of the twins (OR=3.370, 95%CI 1.500-7.568, P<0.05), and high gestational age at birth was a protective factor against BPD (P<0.05). The conditional logistic regression analysis of group B showed that small-for-gestational-age (SGA) birth was an independent risk factor for BPD in individual twins (OR=5.017, 95%CI 1.040-24.190, P<0.05).CONCLUSIONS:
The development of BPD in twin preterm infants is associated with gestational age, birth weight discordance between the twins, and SGA birth.Key words
Full text:
1
Collection:
01-internacional
Database:
MEDLINE
Main subject:
Twins
/
Bronchopulmonary Dysplasia
/
Infant, Premature
Limits:
Female
/
Humans
/
Male
/
Newborn
Language:
Zh
Journal:
Zhongguo Dang Dai Er Ke Za Zhi
Year:
2024
Type:
Article