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Genomic patterns of somatic mutations provide new prognostic, therapeutic, and biological insights in cancer.
Tseitline, Dana; Cohen, Yuval; Adar, Sheera.
Affiliation
  • Tseitline D; The Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
  • Cohen Y; The Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel.
  • Adar S; The Department of Microbiology and Molecular Genetics, Institute for Medical Research Israel-Canada, The Faculty of Medicine, The Hebrew University of Jerusalem, Jerusalem, Israel. Electronic address: sheera.adar@mail.huji.ac.il.
Cell Genom ; 4(8): 100635, 2024 Aug 14.
Article in En | MEDLINE | ID: mdl-39146802
ABSTRACT
The mutational landscape of an individual's cancer can inform on its molecular state and be used as prognostic and therapeutic markers. The study by Barbour et al.1 analyzes mutational patterns in bladder cancer samples to uncover new biological insights into the ERCC2 gene function and develop new predictive prognostic tools.
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Mutation Limits: Humans Language: En Journal: Cell Genom Year: 2024 Type: Article Affiliation country: Israel
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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Urinary Bladder Neoplasms / Mutation Limits: Humans Language: En Journal: Cell Genom Year: 2024 Type: Article Affiliation country: Israel