Ionizable networks mediate pH-dependent allostery in SH2 signaling proteins.

Van Dyck, Papa Kobina; Piszkin, Luke; Gorski, Elijah A; Nascimento, Eduarda Tartarella; Abebe, Joshua A; Hoffmann, Logan M; Peng, Jeffrey W; White, Katharine A.

Affiliation

Van Dyck PK; Department of Chemistry and Biochemistry, University of Notre Dame 251 Nieuwland Science Hall Notre Dame, IN 46556 USA.
Piszkin L; Harper Cancer Research Institute, University of Notre Dame 1234 N. Notre Dame Avenue South Bend, IN 46617 USA.
Gorski EA; Department of Chemistry and Biochemistry, University of Notre Dame 251 Nieuwland Science Hall Notre Dame, IN 46556 USA.
Nascimento ET; Department of Chemistry and Biochemistry, University of Notre Dame 251 Nieuwland Science Hall Notre Dame, IN 46556 USA.
Abebe JA; Harper Cancer Research Institute, University of Notre Dame 1234 N. Notre Dame Avenue South Bend, IN 46617 USA.
Hoffmann LM; Department of Chemistry and Biochemistry, University of Notre Dame 251 Nieuwland Science Hall Notre Dame, IN 46556 USA.
Peng JW; Harper Cancer Research Institute, University of Notre Dame 1234 N. Notre Dame Avenue South Bend, IN 46617 USA.
White KA; Saint Mary's College, Notre Dame, IN 46556 USA.

bioRxiv ; 2024 Aug 21.

Article in En | MEDLINE | ID: mdl-39229188

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Type: Article

Full text: 1 Collection: 01-internacional Database: MEDLINE Language: En Journal: BioRxiv Year: 2024 Type: Article