Bleomycin-induced pulmonary fibrosis in hamsters. An alveolar macrophage product increases fibroblast prostaglandin E2 and cyclic adenosine monophosphate and suppresses fibroblast proliferation and collagen production.

Clark, J G; Kostal, K M; Marino, B A

Clark, J G; Kostal, K M; Marino, B A.

J Clin Invest ; 72(6): 2082-91, 1983 Dec.

Article in En | MEDLINE | ID: mdl-6196378

Subject(s)

Collagen/biosynthesis; Cyclic AMP/biosynthesis; Macrophages/metabolism; Prostaglandins E/biosynthesis; Pulmonary Fibrosis/metabolism; Animals; Bleomycin/toxicity; Cell Division; Cricetinae; Culture Media; Dinoprostone; Fibroblasts/metabolism; Fibroblasts/pathology; Male; Pulmonary Fibrosis/chemically induced; Pulmonary Fibrosis/pathology

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Prostaglandins E / Pulmonary Fibrosis / Collagen / Cyclic AMP / Macrophages Limits: Animals Language: En Journal: J Clin Invest Year: 1983 Type: Article

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