Excretion of RNA catabolites by rats with hepatoma transplants.
Cancer Lett
; 22(2): 187-92, 1984 Mar.
Article
in En
| MEDLINE
| ID: mdl-6200207
ABSTRACT
Rats with transplants of Morris Hepatoma 5123 excreted in their urine greater than normal amounts of modified nucleosides and bases, catabolites of RNA. Despite rapid growth of the neoplasm, the elevated levels did not appear until 22 days after inoculation with the tumor. With tumor progression, there were increased levels and number of these catabolites. This study also suggests that the source of the elevated RNA catabolites is mainly from the host RNA rather than from tumor tissue and also that mRNA and rRNA as well as tRNA may contribute to the urinary levels.
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Collection:
01-internacional
Database:
MEDLINE
Main subject:
RNA
/
Liver Neoplasms, Experimental
Limits:
Animals
Language:
En
Journal:
Cancer Lett
Year:
1984
Type:
Article