Membrane-interactive phospholipids inhibit HIV type 1-induced cell fusion and surface gp160/gp120 binding to monoclonal antibody.

Krugner-Higby, L; Goff, D; Edwards, T; Iyer, N; Neufeld, J; Kute, T; Morris-Natschke, S; Ishaq, K; Piantadosi, C; Kucera, L S

Krugner-Higby, L; Goff, D; Edwards, T; Iyer, N; Neufeld, J; Kute, T; Morris-Natschke, S; Ishaq, K; Piantadosi, C; Kucera, L S.

Affiliation

Krugner-Higby L; Department of Comparative Medicine, Wake Forest University Medical Center, Winston-Salem, North Carolina 27157-1064, USA.

AIDS Res Hum Retroviruses ; 11(6): 705-12, 1995 Jun.

Article in En | MEDLINE | ID: mdl-7576930

Subject(s)

Cell Fusion/drug effects; Gene Products, env/metabolism; HIV Envelope Protein gp120/metabolism; HIV-1/drug effects; Phospholipids/pharmacology; Protein Precursors/metabolism; Antibodies, Monoclonal/metabolism; CD4-Positive T-Lymphocytes/virology; Cell Membrane/drug effects; Cell Membrane/virology; Dideoxynucleotides; HIV Antibodies/metabolism; HIV Envelope Protein gp160; Indolizines/pharmacology; Myristic Acid; Myristic Acids/metabolism; Phospholipid Ethers/chemical synthesis; Phospholipid Ethers/pharmacology; Phospholipids/chemical synthesis; Protein Processing, Post-Translational/drug effects; Viral Proteins/biosynthesis; Viral Proteins/metabolism; Virion/metabolism; Zidovudine/analogs & derivatives; Zidovudine/chemical synthesis; Zidovudine/pharmacology

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Collection: 01-internacional Database: MEDLINE Main subject: Phospholipids / Protein Precursors / Gene Products, env / HIV Envelope Protein gp120 / Cell Fusion / HIV-1 Language: En Journal: AIDS Res Hum Retroviruses Journal subject: SINDROME DA IMUNODEFICIENCIA ADQUIRIDA (AIDS) Year: 1995 Type: Article Affiliation country: United States

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