Analysis of mutations in immunoglobulin heavy chain variable region genes of microdissected marginal zone (MGZ) B cells suggests that the MGZ of human spleen is a reservoir of memory B cells.

Dunn-Walters, D K; Isaacson, P G; Spencer, J

Dunn-Walters, D K; Isaacson, P G; Spencer, J.

Affiliation

Dunn-Walters DK; Histopathology Department, University College London Medical School, United Kingdom.

J Exp Med ; 182(2): 559-66, 1995 Aug 01.

Article in En | MEDLINE | ID: mdl-7629512

Subject(s)

B-Lymphocytes/cytology; Gene Rearrangement, B-Lymphocyte, Heavy Chain; Genes, Immunoglobulin; Immunoglobulin Heavy Chains/genetics; Immunologic Memory; Spleen/cytology; Adult; B-Lymphocytes/immunology; Base Sequence; DNA Primers/chemistry; Female; Humans; Male; Molecular Sequence Data; Point Mutation

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Full text: 1 Collection: 01-internacional Database: MEDLINE Main subject: Spleen / Genes, Immunoglobulin / B-Lymphocytes / Gene Rearrangement, B-Lymphocyte, Heavy Chain / Immunoglobulin Heavy Chains / Immunologic Memory Limits: Adult / Female / Humans / Male Language: En Journal: J Exp Med Year: 1995 Type: Article Affiliation country: United kingdom

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