Blockade of endothelin-converting enzyme reduces pulmonary hypertension after cardiopulmonary bypass and circulatory arrest.

Kirshbom, P M; Tsui, S S; DiBernardo, L R; Meliones, J N; Schwinn, D A; Ungerleider, R M; Gaynor, J W

Kirshbom, P M; Tsui, S S; DiBernardo, L R; Meliones, J N; Schwinn, D A; Ungerleider, R M; Gaynor, J W.

Affiliation

Kirshbom PM; Division of Surgery, Duke University Medical Center, Durham, NC 27710, USA.

Surgery ; 118(2): 440-4; discussion 444-5, 1995 Aug.

Article in En | MEDLINE | ID: mdl-7638762

Subject(s)

Cardiopulmonary Bypass; Endothelins/physiology; Heart Arrest, Induced; Hypertension, Pulmonary/etiology; Animals; Arteries; Aspartic Acid Endopeptidases/antagonists & inhibitors; Endothelin-Converting Enzymes; Gases/blood; Glycopeptides/pharmacology; Hemodynamics; Metalloendopeptidases; Postoperative Complications; Pulmonary Circulation/drug effects; Swine; Vascular Resistance/drug effects

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Collection: 01-internacional Database: MEDLINE Main subject: Cardiopulmonary Bypass / Endothelins / Heart Arrest, Induced / Hypertension, Pulmonary Limits: Animals Language: En Journal: Surgery Year: 1995 Type: Article Affiliation country: United States

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